Journal of Critical Care
Volume 21, Issue 1 , Pages 77-78 , March 2006

Diagnosis and treatment of relative adrenal insufficiency: confusing but at a higher level?

References 

  1. Briegel J, Forst H, Haller M, Schelling G, Kilger E, Kuprat G, et al. Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center study. Crit Care Med. 1999;27:723–732
  2. Bollaert PE, Charpentier C, Levy B, Debouverie M, Audibert G, Larcan A. Reversal of late septic shock with supraphysiologic doses of hydrocortisone. Crit Care Med. 1998;26:645–650
  3. Chawla K, et al. Hydrocortisone reverses refractory septic shock. Crit Care Med. 1999;27(Suppl):A33
  4. Annane D, Sebille V, Charpentier C, Bollaert PE, Francois B, Korach JM, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA. 2002;288(7):862–871
  5. Annane D, Bellissant E, Bollaert PE, Briegel J, Keh D, Kupfer Y. Corticosteroids for treating severe sepsis and septic shock [Cochrane Review]. The Cochrane Library 2004; Issue 1.
  6. Ligtenberg JJ, Zijlstra JG. The relative adrenal insufficiency syndrome revisited: which patients will benefit from low-dose steroids?. Curr Opin Crit Care. 2004;10(4):456–460
  7. Ligtenberg JJM, Zijlstra JG. Relative adrenal insufficiency syndrome. In:  Vincent JF editors. Yearbook of intensive care and emergency medicine 2002. Berlin: Springer; 2002;p. 492–498
  8. Bollaert PE. Stress doses of glucocorticoids in catecholamine dependency: a new therapy for a new syndrome?. Int Care Med. 2000;26(1):3–5
  9. Annane D, Sebille V, Troche G, Raphael JC, Gajdos P, Bellissant E. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin. JAMA. 2000;283(8):1038–1045
  10. Van den Berge G, de Zegher F, Bouillon R. Clinical review 95: acute and prolonged critical illness as different neuroendocrine paradigms. J Clin Endocrinol Metab. 1998;83(6):1827–1834
  11. Zaloga GP, Marik P. Hypothalamic-pituitary-adrenal insufficiency. Crit Care Clin. 2001;17(1):25–41
  12. Marik PE. Unraveling the mystery of adrenal failure in the critically ill. Crit Care Med. 2004;32:569–579
  13. Hamrahian AH, Oseni TS, Arafah BM. Measurements of serum free cortisol in critically ill patients. N Engl J Med. 2004;350(16):1629–1638

PII: S0883-9441(05)00192-9

doi: 10.1016/j.jcrc.2005.11.002

Journal of Critical Care
Volume 21, Issue 1 , Pages 77-78 , March 2006

Article Tools