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Journal of Critical Care
Volume 22, Issue 4
, Pages 305-313
, December 2007
Hypercapnic acidosis modulates inflammation, lung mechanics, and edema in the isolated perfused lung
References
- . Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med. 1998;157:294–323
- Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial. JAMA. 1999;282:54–61
- Causes of mortality in patients with the adult respiratory distress syndrome. Am Rev Respir Dis. 1985;132:485–489
- . Multiple system organ failure. Is mechanical ventilation a contributing factor?. Am J Respir Crit Care Med. 1998;157:1721–1725
- . The pulmonary consequences of a deep breath. Respir Physiol. 1982;49:315–324
- . Effect of different ventilator settings on lung mechanics: with special reference to the surfactant system. Appl Cardiopulm Pathophysiol. 1992;5:117–127
- . Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med. 2000;342:1301–1308
- . Buffering hypercapnic acidosis worsens acute lung injury. Am J Respir Crit Care Med. 2000;161:141–146
- Protective effects of hypercapnic acidosis on ventilator-induced lung injury. Am J Respir Crit Care Med. 2001;164:802–806
- Hypercapnic acidosis may attenuate acute lung injury by inhibition of endogenous xanthine oxidase. Am J Respir Crit Care Med. 1998;158:1578–1584
- Therapeutic hypercapnia reduces pulmonary and systemic injury following in vivo lung reperfusion. Am J Respir Crit Care Med. 2000;162:2287–2294
- Hypercapnic acidosis is protective in an in vivo model of ventilator-induced lung injury. Am J Respir Crit Care Med. 2002;166:403–408
- Effects of therapeutic hypercapnia on mesenteric ischemia-reperfusion injury. Am J Respir Crit Care Med. 2003;168:1383–1390
- Hypercapnic acidosis attenuates endotoxin-induced acute lung injury. Am J Respir Crit Care Med. 2004;169:46–56
- Permissive hypercapnia—role in protective lung ventilatory strategies. Intensive Care Med. 2004;30:347–356
- . Permissive hypercapnia. How permissive should we be?. Am J Respir Crit Care Med. 1994;150:1722–1737
- Endotoxin induces respiratory failure and increases surfactant turnover and respiration independent of alveolocapillary injury in rats. Am J Respir Crit Care Med. 2002;165:1516–1525
- Lung function, permeability, and surfactant composition in oleic acid–induced acute lung injury in rats. Am J Physiol. 2000;279:L1091–L1102
- . A rapid method of total lipid extraction and purification. Can J Med Sci. 1959;37:911–917
- . Phosphorus assay in column chromatography. J Biol Chem. 1959;234:466–468
- . Isolation of disaturated phosphatidylcholine with osmium tetroxide. J Lipid Res. 1976;17:281–284
- . Surfactant-associated 15- and 35-kDa proteins are concentrated in different organelles in rat lung tissue. Exp Lung Res. 1988;14:209–224
- Analysis of pulmonary phospholipid compartments in the unanesthetized rat during prolonged periods of hyperpnea. Exp Lung Res. 1986;11:105–128
- Hypercapnia via reduced rate and tidal volume contributed to lipopolysaccharide-induced lung injury. Am J Respir Crit Care Med. 2005;171(2):147–157
- pH and LPS alters TNF-α release from alveolar type II cells. Am J Respir Crit Care Med. 2001;163:A276;[abstr]
- CO2 alters cytokine release from alveolar macrophages. Am J Respir Crit Care Med. 2002;165:A546;[abstr]
- Therapeutic hypercapnia is not protective in the in vivo surfactant-depleted rabbit lung. Pediatr Res. 2004;55:42–49
- Carbon dioxide attenuates pulmonary impairment resulting from hyperventilation. Crit Care Med. 2003;31:2634–2640
- Hypercapnic acidosis attenuates endotoxin-induced nuclear factor–[kappa]B activation. Am J Respir Cell Mol Biol. 2003;29:124–132
- . Carbon dioxide and the critically ill—too little of a good thing?. Lancet. 1999;354:1283–1286
- On the role of surface tension in the pathophysiology of emphysema. Am J Respir Crit Care Med. 2005;171:300–304
- . Exocytosis of lung surfactant: from the secretory vesicle to the air-liquid interface. Annu Rev Physiol. 2005;67:595–621
- . Molecular and cellular processing of lung surfactant. FASEB J. 1994;8:957–967
- . Mechanical ventilation of rat lung: effect on surfactant forms. Am J Physiol. 1999;277:320–326
- . Effect of pattern of breathing on subfractions of surfactant in tissue and alveolar compartments of the adult rat lung. Am J Respir Cell Mol Biol. 1990;3:251–258
- . Turnover of cholesterol and dipalmitoylphosphatidylcholine in surfactant of adult rat lung. Lipids. 1993;28:173–179
- Changes in surfactant pools after a physiological increase in alveolar surfactant. J Appl Physiol. 1987;63:1902–1911
- Increased surface tension favors pulmonary edema formation in anesthetized dogs' lungs. J Clin Invest. 1979;63:1015–1018
- Biexponential pulmonary clearance of 99mTc-DTPA induced by detergent aerosol. J Appl Physiol. 1994;77:190–196
- Mechanical ventilation of isolated septic rat lungs: effects on surfactant and inflammatory cytokines. J Appl Physiol. 2001;91:811–820
- Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest. 1997;99:944–952
- . Injurious ventilation induces widespread pulmonary epithelial expression of tumor necrosis factor–alpha and interleukin-6 messenger RNA. Crit Care Med. 2002;30:1693–1700
- . Production of inflammatory cytokines in ventilator-induced lung injury: a reappraisal. Am J Respir Crit Care Med. 2001;163:1176–1180
- Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome. Am J Respir Crit Care Med. 1996;154:602–611
- . Inflammatory cytokines in the BAL of patients with ARDS. Persistent elevation over time predicts poor outcome. Chest. 1995;108:1303–1314
- Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS. Plasma IL-1 beta and IL-6 levels are consistent and efficient predictors of outcome over time. Chest. 1995;107:1062–1073
- Hyperventilation induces release of cytokines from perfused mouse lung. Am J Respir Crit Care Med. 1998;157:263–272
- . Mechanical ventilation affects local and systemic cytokines in an animal model of acute respiratory distress syndrome. Am J Respir Crit Care Med. 1999;160:109–116
- . Loss of compartmentalization of alveolar tumor necrosis factor after lung injury. Am J Respir Crit Care Med. 1994;149:1107–1111
- . Acute ventilator-induced vascular permeability and cytokine responses in isolated and in situ mouse lungs. J Appl Physiol. 2004;97(6):2190–2199
- . Partitioning lung and plasma proteins: circulating surfactant proteins as biomarkers of alveolocapillary permeability. Clin Exp Pharmacol Physiol. 1999;26:185–197
☆ This research was supported by the National Health and Medical Research Council of Australia (Canberra, Australian Capital Territory) through grant no. 229954.
PII: S0883-9441(06)00215-2
doi: 10.1016/j.jcrc.2006.12.002
© 2007 Elsevier Inc. All rights reserved.
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Journal of Critical Care
Volume 22, Issue 4
, Pages 305-313
, December 2007
