Journal of Critical Care
Volume 22, Issue 4 , Pages 285-289 , December 2007

Venous thromboembolism in critical illness in a community intensive care unit

  • John G. Muscedere, MD, FRCPC

      Affiliations

    • Department of Medicine, Kingston General Hospital and Queen's University, Kingston, Ontario, Canada K7L 2V7
    • Corresponding Author InformationCorresponding author. Kingston General Hospital, Kingston, Ontario, Canada K7L 2V7.
    • ,
  • Daren K. Heyland, MD, FRCPC, MSc

      Affiliations

    • Department of Medicine, Kingston General Hospital and Queen's University, Kingston, Ontario, Canada K7L 2V7
    • ,
  • Deborah Cook, MD, FRCPC, Msc

      Affiliations

    • McMaster University, Hamilton, Canada

References 

  1. Dhainaut JF. Introduction to the Margaux Conference on Critical Illness: activation of the coagulation system in critical illness. Crit Care Med. 2000;28:S1–S3
  2. Geerts WH. A prospective study of venous thrombo-embolism after major trauma. N Eng J Med. 1994;331:1601–1606
  3. Joynt GM, Kew J, Gomersall CD, Leung VY, Liu EK. Deep venous thrombosis caused by femoral venous catheters in critically ill adult patients. Chest. 2000;178–183
  4. Attia J, Ray JG, Cook DJ, Douketis J, Ginsberg JS, Geerts WH. Deep vein thrombosis and its prevention in critically ill adults. Arch Intern Med. 2001;161:1268–1279
  5. Cook D, Crowther M, Meade M, Rabbat C, Griffith L, Schiff D, et al. Deep venous thrombosis in medical-surgical critically ill patients: prevalence, incidence, and risk factors. Crit Care Med. 2005;33(7):1565–1571
  6. Williams MT, Aravindan N, Wallace MJ, Riedel BJCJ, Shaw ADS. Venous thromboembolism in the intensive care unit. Crit Care Clin. 2003;19(2):185–207
  7. Crowther M, Cook DJ, Griffith L, Devereaux PJ, Rabbat C, Clarke FJ, et al. Deep vein thrombosis: clinically silent in the ICU. J Crit Care. 2005;20(5):334–340
  8. Limpus A, Chaboyer W, McDonald E, Thalib L. Mechanical thromboprophylaxis in critically ill patients: a systematic review and meta-analysis. Am J Crit Care. 2006;15:402–412
  9. Ibrahim EH, Iregui M, Prentice D, Sherman G, Kollef MH, Shannon W. Deep vein thrombosis during prolonged mechanical ventilation despite prophylaxis. Crit Care Med. 2002;30:771–774
  10. Patel R, Cook DJ, Meade MO, Griffith L, Mehta S, Rocker G, et al. for the BITEC Investigators and the Canadian Critical Care Trials Group Burden of Illness: Thrombo-Embolism in Critical Care (BITEC) Study. J Crit Care. 2005;20(4):341–347
  11. Geerts W, Cook D, Selby R, Etchells E. Venous thromboembolism and its prevention in critical care. J Crit Care. 2002;17:95–104
  12. Samama M, Cohen A, Darmon J, et al. A comparison of enoxaparin with placebo for the prevention of venous thrombo-embolism in acutely ill medical patients. N Engl J Med. 1999;341:793–800
  13. Nicolaides AN, Miles C, Hoare M, Jury P, Helmis E, Venniker R. Intermittent sequential pneumatic compression of the legs and thromboembolism-deterrent stockings in the prevention of postoperative deep venous thrombosis. Surgery. 1983;94:21
  14. Hansberry KL, Thompson IM, Bauman J, Deppe S, Rodriguez FR. A prospective comparison of thromboembolic stockings, external sequential pneumatic compression stockings and heparin sodium/dihydroergotamine mesylate for the prevention of thromboembolic complications in urological surgery. J Urol. 1991;145:1205
  15. Kurtoglu M, Yanar H, Bilsel Y, Guloglu R, Kizilirmak S, Buyukkurt D, et al. Venous thromboembolism prophylaxis after head and spinal trauma: intermittent pneumatic compression devices versus low molecular weight heparin. World J Surg. 2004;28(8):807–811
  16. Geerts WH, Pineo GF, Heit JA, Bergqvist D, Lassen MR, Colwell CW, et al. Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126(3):338S–400S
  17. Geerts W, Cook D, Selby R, Etchells E. Venous thromboembolism and its prevention in critical care. J Crit Care. 2002;17:95–104

☆ Data collection was conducted at Hotel-Dieu Grace Hospital, Windsor, Ontario, Canada. Data analysis and manuscript preparation performed at Queen's University, Kingston, Canada, and McMaster University, Hamilton, Canada.

☆☆ This study was supported by the Physician's Services Incorporated Foundation of Ontario, Ontario, Canada.

★ J Muscedere and D Cook received study medication from Pfizer, Inc (Kirkland, Quebec, Canada) for use in a peer-review funded randomized trial testing heparin thromboprophylaxis. D. Cook received an arm's-length grant-in-aid from Pfizer, Inc for an unrelated observational study on thromboprophylaxis. D. Heyland has no conflicts to disclose.

PII: S0883-9441(07)00040-8

doi: 10.1016/j.jcrc.2007.02.003

Journal of Critical Care
Volume 22, Issue 4 , Pages 285-289 , December 2007

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