Journal of Critical Care
Volume 22, Issue 4 , Pages 314-318 , December 2007

Adrenal insufficiency in early phase of pediatric acute lung injury/acute respiratory distress syndrome

  • Rujipat Samransamruajkit, MD

      Affiliations

    • Respiratory and Critical Care unit, Faculty of Medicine, Department of Pediatrics, Chulalongkorn University, Bangkok 10330, Thailand
    • Corresponding Author InformationCorresponding author. Pediatric pulmonary & Critical Care Division, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330 Thailand. Tel.: +66 2 256 4996x129, 123; fax: +66 2 256 4911.
    • ,
  • Siriwan Jitchaiwat, MD

      Affiliations

    • Faculty of Medicine, Department of Pediatrics, Chulalongkorn University, Bangkok 10330, Thailand
    • ,
  • Jitladda Deerojanawong, MD

      Affiliations

    • Respiratory and Critical Care unit, Faculty of Medicine, Department of Pediatrics, Chulalongkorn University, Bangkok 10330, Thailand
    • ,
  • Suchada Sritippayawan, MD

      Affiliations

    • Respiratory and Critical Care unit, Faculty of Medicine, Department of Pediatrics, Chulalongkorn University, Bangkok 10330, Thailand
    • ,
  • Nuanchan Praphal, MD

      Affiliations

    • Respiratory and Critical Care unit, Faculty of Medicine, Department of Pediatrics, Chulalongkorn University, Bangkok 10330, Thailand

References 

  1. Quiney N, Durkin M. Adrenocortical failure in intensive care. BMJ. 1995;310:1253–1254
  2. Lamberts S, Bruining H, De Jong F. Corticosteroids therapy in severe illness. N Engl J Med. 1997;337:1285–1292
  3. Thompson BT. Glucocorticoids and acute lung injury. Crit Care Med. 2003;31(4 Suppl):S253–S257
  4. Chirousos G. Seminars in medicine of the Beth Israel Hospital, The hypothalamic-pituitary-adrenal axis and immune mediated inflammation. N Engl J Med. 1995;332:1351–1362
  5. Cooper MS, Stewart PM. Corticosteroid insufficiency in acutely ill patients. N Engl J Med. 2003;348(8):727–734
  6. Suter PM. Lung inflammation in ARDS—friend or foe?. N Engl J Med. 2006;354:1739–1742
  7. Meduri G, Kantangat S. Glucocorticoid treatment of sepsis and acute respiratory distress syndrome: time for a critical reappraisal. Crit Care Med. 1998;26:630–633
  8. Gonzalez H, Nardi O, Annane D. Relative adrenal failure in the ICU: an identifiable problem requiring treatment. Crit Care Clin 2006;22(1):105-18, vii.
  9. Steinberg KP, Hudson LD, Goodman RB, Hough CL, Lanker PN, et al. The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med. 2006;354(16):1671–1684
  10. Pizarro CF, Troster EJ, Damiani D, et al. Absolute and relative adrenal insufficiency in children with septic shock. Crit Care Med. 2005;33(4):855–859
  11. Agus M. One step forward: an advance in understanding of adrenalinsufficiency in the pediatric critically ill. Crit Care Med. 2005;33(4):911–912
  12. Annane D. Glucocorticoids in the treatment of severe sepsis and septic shock. Curr Opin Crit Care. 2005;11(5):449–453
  13. Ware L, Matthay MA. The acute respiratory distress syndrome. N Engl J Med. 2000;342:1334–1349
  14. Annane D, Sebille V, Troche G, et al. A 3 level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin. JAMA. 2000;283:1038–1045
  15. Hatherill M, Tibby S, Hillard T, et al. Adrenal insufficiency in septic shock. Arch Dis Child. 1999;80:51–55
  16. Annane D, Sebille V, Charpentier C, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA. 2002;288:862–871
  17. Yildiz O, Doganay M, Aygen B, et al. Physiologic dose steroid therapy in sepsis. Crit Care. 2002;6:251–258
  18. Prigent H, Maxime V, Annane D. Clinical review: corticotherapy in sepsis. Crit Care. 2004;8:122–129
  19. Sprung C, Caralis P, Marcial E, et al. The effect of high dose corticosteroids in patients with septic shock. N Engl J Med. 1984;311:1137–1143
  20. Bernard GR, Luuce J, Sprung C. High dose corticosteroids in patients with the ARDS. N Engl J Med. 1987;317:1565–1570
  21. Meduri G, Chinn A, Leeper K, et al. Corticosteroids rescue treatment of progressive fibroproliferation in late ARDS: patterns of response and predictors of outcome. Chest. 1994;105:1516–1527

 Part of this work was presented at the American Thoracic Society meeting, May 2006, San Diego, Calif.

PII: S0883-9441(07)00043-3

doi: 10.1016/j.jcrc.2007.03.003

Journal of Critical Care
Volume 22, Issue 4 , Pages 314-318 , December 2007

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