Journal of Critical Care
Volume 23, Issue 4 , Pages 455-460 , December 2008

Implementation of the Surviving Sepsis Campaign guidelines for severe sepsis and septic shock: We could go faster

  • Massimo Zambon, MD

      Affiliations

    • Department of Anesthesiology and Intensive Care, Cattinara Hospital, University of Trieste, Italy 447-34149
    • ,
  • Marcello Ceola, MD

      Affiliations

    • Department of Intensive Care, Erasme Hospital, Free University of Brussels, 1070 Brussels, Belgium
    • ,
  • Roberto Almeida-de-Castro, MD

      Affiliations

    • Department of Anesthesiology and Intensive Care, Cattinara Hospital, University of Trieste, Italy 447-34149
    • ,
  • Antonino Gullo, MD

      Affiliations

    • Department of Anesthesiology and Intensive Care, Cattinara Hospital, University of Trieste, Italy 447-34149
    • ,
  • Jean-Louis Vincent, MD, PhD

      Affiliations

    • Department of Intensive Care, Erasme Hospital, Free University of Brussels, 1070 Brussels, Belgium
    • Corresponding Author InformationCorresponding author. Tel.: +32 2 555 3380; fax: +32 2 555 4555.

References 

  1. Vincent JL, Sakr Y, Sprung CL, et al. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med. 2006;34:344–353
  2. Dellinger RP, Carlet JM, Masur H, et al. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med. 2004;32:858–873
  3. Levy MM, Pronovost PJ, Dellinger RP, et al. Sepsis change bundles: converting guidelines into meaningful change in behavior and clinical outcome. Crit Care Med. 2004;32:S595–S597
  4. Gao F, Melody T, Daniels DF, et al. The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study. Crit Care. 2005;9:R764–R770
  5. Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intensive Care Med. 2003;29:530–538
  6. Brunkhorst FM, Kuhnt E, Engel C, et al. Intensive insulin therapy in patient with severe sepsis and septic shock is associated with an increased rate of hypoglycemia—results from a randomized multicenter study (VISEP). Infection. 2005;33(Suppl 1):19;[abst]
  7. Malhotra A. Intensive insulin in intensive care. N Engl J Med. 2006;354:516–518
  8. Trzeciak S, Dellinger RP, Abate NL, et al. Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department. Chest. 2006;129:225–232
  9. Kortgen A, Niederprum P, Bauer M. Implementation of an evidence-based “standard operating procedure” and outcome in septic shock. Crit Care Med. 2006;34:943–949
  10. Shapiro NI, Howell MD, Talmor D, et al. Implementation and outcomes of the Multiple Urgent Sepsis Therapies (MUST) protocol. Crit Care Med. 2006;34:1025–1032
  11. Kumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006;34:1589–1596
  12. Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001;345:1368–1377
  13. Vincent JL, Bernard GR, Beale R, et al. Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE. Crit Care Med. 2005;33:2266–2277

PII: S0883-9441(07)00107-4

doi: 10.1016/j.jcrc.2007.08.003

Journal of Critical Care
Volume 23, Issue 4 , Pages 455-460 , December 2008

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