Journal of Critical Care
Volume 23, Issue 3 , Pages 440-444 , September 2008

Microsatellite polymorphism of the human leptin gene and risk of obesity

References 

  1. Friedrich MJ. Epidemic of obesity expands its spread to developing countries. JAMA. 2002;287:1382–1386
  2. Flegal KM, Carroll MD, Kuczmarski RJ, et al. Overweight and obesity in the United States: prevalence and trends, 1960-1994. Int J Obes Relat Metab Disord. 1998;22:39–47
  3. Froguel P, Boutin P. Genetics of pathways regulating body weight in the development of obesity in humans. Exp Biol Med. 2001;226:991–996
  4. Lean MEJ, Hans TS, Seidell JC. Impairment of health and quality of life in people with large waist circumference. Lancet. 1998;351:853–856
  5. Isse N, Ogawa Y, Tamura N, et al. Structural organization and chromosomal assignment of the human obese gene. J Boil Chem. 1995;270:27728–27733
  6. World Health Organization . Preventing and managing the Global Epidemic. Geneva: World Health Organization; 1998;
  7. Lean MEJ. Morrison waist circumference as a measure for indicating need for weight management. BMJ. 1995;311:
  8. Rifal N, Bachorik PS, Albers JJ. Lipids, lipoproteins and apolipoproteins. In:  Burtis CA,  Ashwood ER editor. Tietz text book of clinical chemistry. 3rd ed.. Philadelphia: W.B Saunders Company; 1999;p. 809–861
  9. Allain CC, et al. Enzymatic determination. Clin Chem. 1974;20:470
  10. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifugation. Clin Chem. 1997;18:499–502
  11. Josef S, David WR, Nina I, et al. In: Molecular cloning: rapid isolation of mammalian DNA. New York: Cold Spring Harbour Laboratory Press; 2002;p. 628–630
  12. Emery AE. Methodology in medical genetics- an introduction to statistical methods. Edinburgh: Longman; 1986;
  13. Karine C, Chad G, Jorg H, et al. Indication for linkage of human OB gene region with extreme obesity. Cell. 1996;45:687–690
  14. Clement K, Garner C, Hager J, et al. Indication for linkage of the human OB gene region with extreme obesity. Diabetes. 1996;45:687–690
  15. Shintani M, Ikegami H, Yamato E, et al. A novel microsatellite polymorphism in the human OB gene: a highly polymorphic marker for linkage analysis. Diabetologia;. 1996;39:1398–1401
  16. Danielle RR, Yuan D, Weizhen X, et al. Extreme obesity may be linked to markers flanking the human OB gene. Diabetes. 1996;45:691–694
  17. Shintani M, Ikegami H, Tomomi F, et al. Leptin gene polmorphism Is associated with Hypertension Independent of obesity. 2002;87:2909-2912.

PII: S0883-9441(08)00144-5

doi: 10.1016/j.jcrc.2008.06.007

Journal of Critical Care
Volume 23, Issue 3 , Pages 440-444 , September 2008