Journal of Critical Care
Volume 25, Issue 1 , Pages 69-77, March 2010

Pharmacodynamic-based clinical pathway for empiric antibiotic choice in patients with ventilator-associated pneumonia☆

  • Anthony M. Nicasio, PharmD

      Affiliations

    • Center for Antiinfective Research and Development, Hartford Hospital, Hartford, CT 06102, USA
    • ,
  • Kathryn J. Eagye, MPH

      Affiliations

    • Center for Antiinfective Research and Development, Hartford Hospital, Hartford, CT 06102, USA
    • ,
  • David P. Nicolau, PharmD, FCCP, FIDSA

      Affiliations

    • Center for Antiinfective Research and Development, Hartford Hospital, Hartford, CT 06102, USA
    • Division of Infectious Diseases, Hartford Hospital, Hartford, CT, USA
    • ,
  • Eric Shore, MD

      Affiliations

    • Division of Pulmonary/Critical Care, Hartford Hospital, Hartford, CT, USA
    • University of Connecticut, School of Medicine, Farmington, CT 06030, USA
    • ,
  • Marc Palter, MD

      Affiliations

    • Division of Neurosurgery/Critical Care, Hartford Hospital, Hartford, CT, USA
    • ,
  • Judith Pepe, MD

      Affiliations

    • Division of Surgery/Critical Care, Hartford Hospital, Hartford, CT, USA
    • University of Connecticut, School of Medicine, Farmington, CT 06030, USA
    • ,
  • Joseph L. Kuti, PharmD

      Affiliations

    • Center for Antiinfective Research and Development, Hartford Hospital, Hartford, CT 06102, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 860 545 3612; fax: +1 860 545 3992.

published online 08 May 2009.

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☆ This study was partially funded by AstraZeneca Pharmaceuticals LP, Wilmington, Del. E-test strips were graciously donated by AB Biodisk, Solna, Sweden. Drs Nicolau and Kuti are members of the speakers bureau, hired as consultants, and received research funding from AstraZeneca LP. All other authors have nothing to disclose.

PII: S0883-9441(09)00072-0

doi:10.1016/j.jcrc.2009.02.014

Journal of Critical Care
Volume 25, Issue 1 , Pages 69-77, March 2010

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