Journal of Critical Care
Volume 26, Issue 2 , Pages 186-192 , April 2011

Clinical characteristics and outcomes of patients with 2009 influenza A(H1N1) virus infection with respiratory failure requiring mechanical ventilation

  • Nicolás Nin, MD, PhD

      Affiliations

    • Hospital Universitario de Getafe & CIBER de Enfermedades Respiratorias, Madrid, Spain
    • ,
  • Luis Soto, MD

      Affiliations

    • Instituto Nacional del Tórax, Santiago de Chile, Chile
    • ,
  • Javier Hurtado, MD

      Affiliations

    • Hospital Español Juan J Crottogini, Montevideo, Uruguay
    • ,
  • José A. Lorente, MD, PhD

      Affiliations

    • Hospital Universitario de Getafe & CIBER de Enfermedades Respiratorias, Madrid, Spain
    • ,
  • María Buroni, MD

      Affiliations

    • Hospital Español Juan J Crottogini, Montevideo, Uruguay
    • ,
  • Francisco Arancibia, MD

      Affiliations

    • Instituto Nacional del Tórax, Santiago de Chile, Chile
    • ,
  • Sebastian Ugarte, MD

      Affiliations

    • Clínica Indisa, Santiago de Chile, Chile
    • ,
  • Homero Bagnulo, MD

      Affiliations

    • Hospital Maciel, Montevideo, Uruguay
    • ,
  • Pablo Cardinal, MD

      Affiliations

    • Sanatorio CASMU, Montevideo, Uruguay
    • Hospital Central de las Fuerzas Armas, Montevideo, Uruguay
    • ,
  • Guillermo Bugedo, MD

      Affiliations

    • Universidad Católica de Chile, Santiago, Chile
    • ,
  • Estrella Echevarría, MD

      Affiliations

    • Hospital Maciel, Montevideo, Uruguay
    • ,
  • Alberto Deicas, MD

      Affiliations

    • Hospital Central de las Fuerzas Armas, Montevideo, Uruguay
    • ,
  • Carlos Ortega, MD

      Affiliations

    • Hospital Regional de Concepción, Concepción, Chile
    • ,
  • Fernando Frutos-Vivar, MD

      Affiliations

    • Hospital Universitario de Getafe & CIBER de Enfermedades Respiratorias, Madrid, Spain
    • ,
  • Andrés Esteban, MD, PhD

      Affiliations

    • Hospital Universitario de Getafe & CIBER de Enfermedades Respiratorias, Madrid, Spain
    • Corresponding Author InformationCorresponding author. Servicio de Medicina Intensiva, Hospital Universitario de Getafe, Carretera de Toledo, Getafe, 28905 Madrid, Spain. Tel.: +34 916834982; fax: +34 916832095.

References 

  1. The ANZIC Influenza Investigators . Critical care services and 2009 H1N1 influenza in Australia and New Zealand. JAMA. 2009;361:1925–1934
  2. Rello J, Rodríguez A, Ibanez P, Socias L, Cebrian J, Marques A, et al. H1N1 SEMICYUC Working Group Intensive care adult patients with severe respiratory failure caused by influenza A (H1N1) in Spain. Crit Care. 2009;13:R148
  3. Centers for Disease Control and Prevention (CDC) . Swine influenza A (H1N1) infection in two children—Southern California. March-April 2009. MMWR Morb Mortal Wkly Rep. 2009;58:400–402
  4. Pandemic (H1N1). Geneva: World Health Organization. (Accessed November 20, 2009, at http://www.who.int/csr/disease/swineflu/en/index.html)
  5. Domínguez-Cherit G, Lapinsky SE, Macias AE. Critically ill patients with 2009 influenza A(H1N1) in Mexico. JAMA. 2009;302:E1–E8
  6. Kumar A, Zarychanski R, Pinto R, Cook DJ, Marshall J, Lacroix J, et al. Canadian Critical Care Trials Group H1N1 Collaborative Critically ill patients with 2009 influenza A(H1N1) infection in Canada. JAMA. 2009;302:E1–E8
  7. Jain S, Kamimoto L, Bramley AM, Schmitz AM, Benoit SR, Louie J, et al Hospitalized patients with 2009 H1N1 influenza in the United State, April-June 2009. N Eng J Med. 2009;361:1935–1944
  8. Vincent JL, de Mendonca A, Cantraine F, Moreno R, Takala J, Suter PM, et al. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Crit Care Med. 1998;26:1793–1800
  9. Novel-Swine Origin 2009 Influenza A(H1N1) Virus Investigation Team . Emergence of a novel swine origin 2009 influenza A(H1N1) virus in humans. N Engl J Med. 2009;360:2605–2615
  10. Chowell G, Bertozzi SM, Colchero MA, Lopez-Gatell H, Alpuche-Aranda C, Hernandez M, et al. Severe respiratory disease concurrent with the circulation of H1N1 influenza. N Engl J Med. 2009;361:674–679
  11. Miller MA, Viboud C, Olson DR, Grais RF, Rabaa MA, Simonsen L. Prioritization of influenza pandemic vaccination to minimize years of life lost. J Infect Disease. 2008;198:305–311
  12. Centers for Disease Control and Prevention (CDC) . Serum cross-reactive antibody response to a novel influenza A (H1N1) virus after vaccination with seasonal vaccine. MMWR Morb Mortal Wkly Rep. 2009;58:521–524
  13. Fisman DN, Savage R, Achonu C, Akwar H, Farrell DJ, Crowcorft NS. Older age and reduced likelihood of 2009 influenza A(H1N1) virus infection. N Eng J Med. 2009;361:2000–2001
  14. Jamieson DJ, Honein MA, Rasmussen SA, Jamieson DJ, Honein MA, Rasmussen SA, et al. Novel Influenza A (H1N1) Pregnancy Working Group H1N1 2009 influenza virus infection during pregnancy in the USA. LANCET. 2009;374:451–458
  15. Mauad T, Hajjar LA, Callegari GD, da Silva LF, Schout D, Galas FR, et al. Lung pathology in fatal novel human influenza A (H1N1) infection. Am J Respir Crit Care Med. 2009;29:[in press]
  16. Esteban A, Ferguson ND, Meade MO, et al. Evolution of mechanical ventilation in response to clinical research. Am J Respir Crit Care Med. 2008;177:170–177
  17. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5838a4.htm, visited on December 1, 2009.

PII: S0883-9441(10)00159-0

doi: 10.1016/j.jcrc.2010.05.031

Journal of Critical Care
Volume 26, Issue 2 , Pages 186-192 , April 2011

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