Journal of Critical Care
Volume 26, Issue 1 , Pages 89-94 , February 2011

Off-label medication use in adult critical care patients

  • Ishaq Lat, PharmD

      Affiliations

    • University of Chicago Medical Center, Chicago, IL 60637, USA
    • Corresponding Author InformationCorresponding author.
    • ,
  • Scott Micek, PharmD

      Affiliations

    • Barnes-Jewish Hospital, St Louis, MO 63110, USA
    • ,
  • Jeffrey Janzen, BA

      Affiliations

    • Via Christi Regional Medical Center, Department of Research, Wichita, KS 67218, USA
    • ,
  • Henry Cohen, PharmD

      Affiliations

    • Long Island University, Long Island, NY 11201, USA
    • Kingsbrook Jewish Medical Center, Brooklyn, NY 11201, USA
    • ,
  • Keith Olsen, PharmD

      Affiliations

    • University of Nebraska Medical Center, Omaha, NE 68131, USA
    • ,
  • Curtis Haas, PharmD

      Affiliations

    • University of Rochester Medical Center, Rochester, NY 14642, USA

References 

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  15. Annane D, Briegel J, Keh D, et al. Clinical equipoise remains for issues of adrenocorticotropic hormone administration, cortisol testing, and therapeutic use of hydrocortisone. Crit Care Med. 2003;31(8):2250–2251
  16. Martin GS, Mannino DM, Eaton S, et al. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med. 2003;348:1546–1554
  17. MacLaren R, Weber LA, Brake H, et al. A multi-center assessment of recombinant factor VIIa off-label usage: clinical experiences and associated outcomes. Transfusion. 2005;45:1434–1442
  18. Vincent JL, Bihari D, Suter PM, et al. The prevalence of nosocomial infection in intensive care units in Europe: results of the European Prevalence of Infection in Intensive Care (EPIC) study. JAMA. 1995;274:639–644
  19. Vincent JL, Rello J, Marshall J, et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA. 2009;302:2323–2329

☆ Financial support: This study was funded in part by the University of Chicago Program for Pharmaceutical Policy.

PII: S0883-9441(10)00175-9

doi: 10.1016/j.jcrc.2010.06.012

Journal of Critical Care
Volume 26, Issue 1 , Pages 89-94 , February 2011

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