Journal of Critical Care
Volume 26, Issue 2 , Pages 201-205 , April 2011

Procalcitonin levels are lower in intensive care unit patients with H1N1 influenza A virus pneumonia than in those with community-acquired bacterial pneumonia. A pilot study

  • Enrique Piacentini, MD

      Affiliations

    • Doctorando UAB, Intensive Care Unit, Hospital Universitario Mútua de Terrassa. Terrassa 08221, Spain
    • Corresponding Author InformationCorresponding author. Tel.: +34 93 726 5050x1244; fax: +34 93 726 5006.
    • ,
  • Baltasar Sánchez, MD

      Affiliations

    • Doctorando UAB, Intensive Care Unit, Hospital Universitario Mútua de Terrassa. Terrassa 08221, Spain
    • ,
  • Vanessa Arauzo, MD

      Affiliations

    • Doctorando UAB, Intensive Care Unit, Hospital Universitario Mútua de Terrassa. Terrassa 08221, Spain
    • ,
  • Esther Calbo, MD

      Affiliations

    • Internal Medicine Department, Hospital Universitario Mútua de Terrassa. Doctorando UAB, 08221, Terrassa, Spain
    • ,
  • Eva Cuchi, MD

      Affiliations

    • CATLAB Microbiología, Hospital Universitario Mútua de Terrassa. 08221, Terrassa, Spain
    • ,
  • Juan Manuel Nava, MD

      Affiliations

    • Doctorando UAB, Intensive Care Unit, Hospital Universitario Mútua de Terrassa. Terrassa 08221, Spain

References 

  1. Domınguez-Cherit G, Lapinsky S, Macias A, et al. Critically ill patients with 2009 influenza A (H1N1) in Mexico. JAMA. 2009;302:1880–1887
  2. Jain S, Kamimoto L, Bramley A, et al. for the 2009 Pandemic Influenza A (H1N1) Virus Hospitalizations Investigation Team Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009. N Engl J Med. 2009;361:1935–1944
  3. Rello J, Rodriguez A, Ibanez P, et al. Intensive care adult patients with severe respiratory failure caused by influenza A (H1N1)v in Spain. Crit Care. 2009;13:R148
  4. Itoh Y, Shinya K, Kiso M, et al. In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Nature. 2009;460:1021–1025
  5. Toikka P, Irjala K, Juvén T, et al. Serum procalcitonin, C-reactive protein and interleukin-6 for distinguishing bacterial and viral pneumonia in children. Pediatr Infect Dis J. 2009;19:598–602
  6. Krüger S, Ewig S, Papassotiriou J, et al. Inflammatory parameters predict etiologic patterns but do not allow for individual prediction of etiology in patients with CAP—results from the German competence network CAPNETZ. Respir Res. 2009;10:65
  7. Hillas G, Vassilakopoulos T, Plantza P, et al. CRP and PCT as predictors of survival and septic shock in ventilator-associated pneumonia. Eur Respir J. 2010;35:725–727
  8. Okimoto N, Hayashi Y, Ishiga M, et al. Procalcitonin and severity of community-acquired pneumonia. J Infect Chemother. 2009;15:426–427
  9. Seligman R, Meisner M, Lisboa T, et al. Decreases in procalcitonin and C-reactive protein are strong predictors of survival in ventilator-associated pneumonia. Crit Care10. 2006;R125
  10. Mandell LA, Wunderink RG, Anzueto A, et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis. 2007;44:S27–S72
  11. Libster R, Bugna J, Coviello S, et al. Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Argentina. N Engl J Med. 2010;362(1):45–55

☆ Drs Enrique Piacentini, Baltasar Sánchez, Vanessa Arauzo, Esther Calbo, Eva Cuchi, and Juan Manuel Nava declare that they have no competing interests.

PII: S0883-9441(10)00187-5

doi: 10.1016/j.jcrc.2010.07.009

Journal of Critical Care
Volume 26, Issue 2 , Pages 201-205 , April 2011

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