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Journal of Critical Care
Volume 21, Issue 1, Pages 1-116 (March 2006)
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Feature: HSR Methodology


Methods to adjust for bias and confounding in critical care health services research involving observational data
Hannah Wunsch, Walter T. Linde-Zwirble, Derek C. Angus
pages 1-7
Abstract | Full Text | Full-Text PDF (119 KB)


Do specialist transport personnel improve hospital outcome in critically ill patients transferred to higher centers? A systematic review
Dean Belway, William Henderson, Sean P. Keenan, Adrian R. Levy, PeterM. Dodek
pages 8-17
Abstract | Full Text | Full-Text PDF (244 KB)


Critical care transport teams: searching for evidence of effectiveness
Andrew C. McDonald
pages 17-18
Full Text | Full-Text PDF (48 KB)

Feature: Evolution of HSR in Critical Care


The evolution of intensive care unit performance assessment
Marius Terblanche, Neill K.J. Adhikari
pages 19-22
Abstract | Full Text | Full-Text PDF (83 KB)

Feature: Critically Appraising Clinical Trials in Critical Care


Clinical trial design—effect of prone positioning on clinical outcomes in infants and children with acute respiratory distress syndrome
Martha A.Q. Curley, John H. Arnold, John E. Thompson, James C. Fackler, Mary Jo Grant, Lori D. Fineman, Natalie Cvijanovich, Frederick E. Barr, Shirley Molitor-Kirsch, David M. Steinhorn, Michael A. Matthay, Patricia L. Hibberd, for the Pediatric Prone Positioning Study Group
pages 23-32
Abstract | Full Text | Full-Text PDF (469 KB)


Clinical trial design in acute respiratory distress syndrome: facing down the complexity
Todd W. Rice, Lorraine B. Ware
pages 32-37
Full Text | Full-Text PDF (91 KB)

Feature: HSR Rounds


Controversies in sepsis clinical trials: proceedings of a meeting of the International Sepsis Forum, Lausanne, Switzerland, September 29, 2001
R. Phillip Dellinger, Edward Abraham, Gordon Bernard, John C. Marshall, Jean-Louis Vincent
pages 38-47
Abstract | Full Text | Full-Text PDF (149 KB)

Clinical Research--Adult


Systemic inflammatory response syndrome and surgical stress in thoracic surgery
Kazumasa Takenaka, Eiji Ogawa, Hiromi Wada, Toshiki Hirata
pages 48-53
Abstract | Full Text | Full-Text PDF (153 KB)


Systemic inflammatory response syndrome and complications after surgery
Marius Terblanche, Stephen J. Brett
pages 53-55
Full Text | Full-Text PDF (61 KB)


Incidence, risk factors, and outcome of ventilator-associated pneumonia
Eva Tejerina, Fernando Frutos-Vivar, Marcos I. Restrepo, Antonio Anzueto, Fekri Abroug, Fernando Palizas, Marco González, Gabriel D'Empaire, Carlos Apezteguía, Andrés Esteban, for the Internacional Mechanical Ventilation Study Group
pages 56-65
Abstract | Full Text | Full-Text PDF (165 KB)


Epidemiology and prognostic factors of critically ill patients treated with hemodiafiltration
Stéphane Soubrier, Olivier Leroy, Patrick Devos, Saad Nseir, Hugues Georges, Thibaud d'Escrivan, Benoit Guery
pages 66-72
Abstract | Full Text | Full-Text PDF (171 KB)


Relative adrenal insufficiency in patients with septic shock; a close look to practice patterns
Naser Elsouri, Joseph Bander, Jorge A. Guzman
pages 73-77
Abstract | Full Text | Full-Text PDF (108 KB)


Diagnosis and treatment of relative adrenal insufficiency: confusing but at a higher level?
Jack J.M. Ligtenberg, Jan G. Zijlstra
pages 77-78
Full Text | Full-Text PDF (53 KB)


Monitoring of subcutaneous dalteparin in patients with renal insufficiency under intensive care: an observational study
Chara Kani, Sophia L. Markantonis, Chara Nicolaou, Nina Maggina
pages 79-84
Abstract | Full Text | Full-Text PDF (188 KB)

Pre-Clinical Research


Multiple-organ effect of normobaric hyperoxia in neonatal rats
Dan Torbati, Gim H. Tan, Stanley Smith, Kendall S. Frazier, Javier Gelvez, Harun Fakioglu, Balagangadhar R. Totapally
pages 85-93
Abstract | Full Text | Full-Text PDF (264 KB)


Hyperoxia and extrapulmonary organ injury: are the neutrophils the culprit or just innocent bystanders?
Jaques Belik
pages 93-94
Full Text | Full-Text PDF (51 KB)

Complexity in ICU


Investigation of altered heart rate variability, nonlinear properties of heart rate signals, and organ dysfunction longitudinally over time in intensive care unit patients
Vasilios E. Papaioannou, Nikos Maglaveras, Ioanna Houvarda, Ellen Antoniadou, George Vretzakis
pages 95-103
Abstract | Full Text | Full-Text PDF (398 KB)


Longitudinal changes in heart rate variability: laying the groundwork for the next generation in clinical monitoring
Brahm Goldstein
pages 103-104
Full Text | Full-Text PDF (49 KB)


Concepts for developing a collaborative in silico model of the acute inflammatory response using agent-based modeling
Gary An
pages 105-110
Abstract | Full Text | Full-Text PDF (204 KB)


Toward a framework for evidence-based modeling
Gilles Clermont
pages 110-111
Full Text | Full-Text PDF (50 KB)

Case Report


Methemoglobinemia and acute hemolysis after tetracaine lozenge use
Sandrine Lavergne, Michael Darmon, Vincent Levy, Elie Azoulay
pages 112-114
Abstract | Full Text | Full-Text PDF (82 KB)

Letter to the Editor


Response to discussion by Dr Philip Hébert free full text
Venkatesh Aiyagari, Michael N. Diringer
pages 115-116
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In reply to Venkatesh Aiyagari and Michael N. Diringer free full text
Philip C. Hébert
page 116
Full Text | Full-Text PDF (38 KB)

Frontmatter


Editorial board free full text
page A2
Full-Text PDF (17 KB)


Table of Contents free full text
pages A3-A4
Full-Text PDF (29 KB)

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